Efficiency of Respirator Filters Against A Viral Aerosol

 

Paul Gardner1, Aaron Richardson2, Kent Hofacre2, and Samy Rengasamy3

 

1 US Army Edgewood Chemical Biological Center

5183 Blackhawk Rd, Bldg E5604, Aberdeen Proving Ground, MD 21010-5424,

E-mail: paul.gardner2@us.army.mil

 

2 Battelle Memorial Institute

505 King Avenue,  Columbus, OH 43201-2693

 

3 National  Personal  Protective Technology Laboratory/NIOSH

626 Cochrans Mill Road

Pittsburgh, PA 15236

 

The growing threat associated with the avian flu virus (H5N1) and other virulent pathogens presents a unique challenge to emergency responders, healthcare workers, and the civilian population.  The use of National Institute for Occupational Safety and Health (NIOSH)-approved particulate respirators, if used according to recommended practices, provides protection against infectious airborne agents in various workplace settings.  Currently, NIOSH certifies respirators based on an inert aerosol test at a constant flow rate of 85 L/min.  However, it has not been well established that these filters provide protection against biological aerosols, especially with regard to viral aerosols.  This study investigated the performance of NIOSH-approved P100 and N95 particulate respirator filters and filtering facepiece masks against the virus MS2 phage, a bacteriophage that is non-pathogenic to humans, aerosolized from a liquid suspension.  Tests were performed under two cyclic flow conditions (minute volumes of 85 and 135 L/min) and two constant flow rates (85 and 270 L/min).  In addition, the measured efficiencies were compared to those measured under similar test conditions with non-biological (inert) test aerosols.  The results suggest that testing with inert particles in the most penetrating particle size range provides a conservative estimate of MS2 phage penetration.